Advise patients to swallow tablets whole. Do not chew, crush, or split WELIREG prior to swallowing.
If a dose of WELIREG is missed, it can be taken as soon as possible on the same day. Resume the regular daily dose schedule for WELIREG the next day. Do not take extra tablets to make up for the missed dose.
If vomiting occurs any time after taking WELIREG, do not retake the dose. Take the next dose on the next day.
Dosage Modifications for Adverse Reactions: Dosage modifications for WELIREG for adverse reactions are summarized in Table 3. (See Table 3.)
The recommended dose reductions are: First dose reduction: WELIREG 80 mg orally once daily.
Second dose reduction: WELIREG 40 mg orally once daily.
Third dose reduction: Permanently discontinue.
