Ursobil Special Precautions

Be advised before patient takes Ursodeoxycholic acid.
Test the liver function regularly every 4 weeks for the first 3 months of treatment. After this time, it should be monitored at 3 months intervals.
When used to dissolve gallstones, arrange for a scan of the gall bladder after the first 6-10 months of treatment.
If Ursodeoxycholic acid will be used for the dissolution of gallstones, be informed in case the patient is taking any medicines that contain oestrogenic hormones, as these medicines stimulate the formation of gallstones.
When used in the treatment of PBC, in rare cases the symptoms may worsen at the beginning of treatment. If this happens, consider reducing the initial dose.
Be informed if the patient has diarrhoea, as this may require a dose reduction or discontinuation of treatment.
Do not exceed the recommended dose. In a clinical trial, the use of high dose ursodeoxycholic acid (28-30mg/kg/day) was associated with higher rates of serious adverse events.
Driving and using machines: No effects on the ability to drive and use machines have been observed.
Use in Children: There are no age restrictions on the use of Ursodeoxycholic acid. The use of Ursodeoxycholic acid depends on body weight and the disease.