Ursobil Drug Interactions

Be advised if the patient is also taking or using medicines with the following active substances. The effects of these medicines may be altered.
A reduction in the effects of Ursodeoxycholic acid is possible when taking it with the following medicines: Cholestyramine, colestipol (used to lower blood lipid levels) or antacids containing aluminium hydroxide or smectite (aluminium oxide) (used to bind stomach acid). If the patient must take medication that contains any of these substances, it must be taken at least two hours before or after Ursodeoxycholic acid.
A reduction in the effects of the following medicines is possible when taking Ursodeoxycholic acid: Ciprofloxacin, and dapsone (antibiotics), nitrendipine (used to treat high blood pressure) and other medicines that are metabolized in a similar way. It may be necessary to alter the dose of these medicines.
A change in the effects of the following medicines is possible when taking Ursodeoxycholic acid: Ciclosporin (to reduce the activity of the immune system). If the patient is being treated with ciclosporin, the amount of ciclosporin in the blood should be checked. If necessary, adjust its dose. Rosuvastatin (for high cholesterol and related conditions).
If Ursodeoxycholic acid will be used for the dissolution of gallstones, be informed in case the patient is taking any medicines that contain oestrogenic hormones or blood cholesterol lowering agents such as clofibrate. These medicines stimulate the formation of gallstones, which is a counter-effect to the treatment with Ursodeoxycholic acid.
Be advised if the patient is taking or using, have recently taken or used or might take or use any other medicine.