Careful Administration: Transamin should be administered with care in the following patients:
Patients with thrombosis (cerebral thrombosis, myocardial infarction or thrombophlebitis, etc) and patients at risk of thrombosis. (Transamin may stabilize thrombosis.)
Patients with consumption coagulopathy (use concomitantly with heparin, etc). (Transamin may stabilize thrombosis.)
Patients with a history of hypersensitivity to tranexamic acid.
Others: Retinal degeneration has been reported with tranexamic acid in dogs after long-term, high-dose administration.
Use in the elderly: Since elderly patients often have reduced physiological function, careful supervision and measures eg, reducing the dose are recommended.