Adults: Capsule/Tablet: The usual dosage for oral use is 750-2000 mg tranexamic acid (as the base) daily in 3 or 4 divided doses. The dosage should be adjusted to individuals according to the patient's age and symptoms.
Daily Dose: 3-8 capsules or 2-4 tablets. To be divided into 3 or 4 portions.
Ampoule: The usual daily dosage for IV or IM injection is 250-500 mg of tranexamic acid in 1 or 2 divided doses. During or after surgery, 500-1000 mg IV or 500-2500 mg by IV drip infusion are administered each time as required.
250 mg/5 mL Ampoule: The usual daily dosage for IV or IM injection is 5-10 mL (1-2 amps) in 1 or 2 divided doses. During or after surgery, 10-50 mL (2-10 amps) are administered each time by IV drip infusion as required.
250 mg/2.5 mL and 1000 mg/10 mL Ampoule: The usual daily dose for IV or IM injection is 2.5-5 mL of tranexamic acid in 1 or 2 divided doses. During or after surgery, 5-10 mL IV or 5-25 mL by IV drip infusion are administered each time as required.
The dosage should be adjusted to individuals according to the patient's age and conditions.
Administration: IV: With regard to IV administration, inject the drug slowly. (Symptoms eg, nausea, chest discomfort, palpitations and a fall in blood pressure may rarely occur.)
IM: With regard to IM injection, pay careful attention to the following points to avoid injuring tissues, nerves, etc.
Inject the drug carefully to avoid contact with nerves.
If repeated injection is required, change the injection site (eg, alternate between the right and left arms). Special care should be observed when the drug is administered to premature infants, newborns, suckling infants and children.
If insertion of the injection needle induces intense pain or if blood flows back into the syringe, withdraw the needle immediately and perform injection at a different site.