Tenovid Drug Interactions

Advise the patient to inform the doctor or pharmacist if the patient is taking, has recently taken or might take any other medicines.
Anti-HIV medicines should not be stopped when the patient starts Tenovid if the patient has both HBV and HIV.
Tenovid should not be taken if the patient is already taking other medicines containing tenofovir disoproxil fumarate or tenofovir alafenamide. Tenovid should not be taken together with medicines containing adefovir dipivoxil (a medicine used to treat chronic hepatitis B).
Advise the patient to inform the doctor if the patient is taking other medicines that may damage the kidneys. These include: aminoglycosides, pentamidine or vancomycin (for bacterial infection); amphotericin B (for fungal infection); foscarnet, ganciclovir, or cidofovir (for viral infection); interleukin-2 (to treat cancer); adefovir dipivoxil (for HBV); tacrolimus (for suppression of the immune system); non-steroidal anti-inflammatory drugs (NSAIDs, to relieve bone or muscle pains).
Other medicines containing didanosine (for HIV infection): Taking Tenovid with other antiviral medicines that contain didanosine can raise the levels of didanosine in the blood and may reduce CD4 cell counts. Rarely, inflammation of the pancreas and lactic acidosis (excess lactic acid in the blood), which sometimes caused death, have been reported when medicines containing tenofovir disoproxil fumarate and didanosine were taken together. Carefully consider whether to treat the patient with combinations of tenofovir and didanosine.
Advise the patient to inform the doctor if the patient is taking ledipasvir/sofosbuvir, sofosbuvir/velpatasvir or sofosbuvir/velpatasvir/voxilaprevir to treat hepatitis C infection.
Tenovid with food and drink: Tenovid should be taken with food (for example, a meal or a snack).