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Oral administration.
Adult: Active duodenal and active benign gastric benign ulcer: 40mg daily at bedtime for 4-8 weeks.
Maintenance therapy for duodenal ulcer: 20mg once a day at bedtime.
Gastro-oesophageal reflux disease (GERD): Initial dose is 20mg to 40mg twice daily for 6 to 12 weeks.
Pathological hypersecretory conditions: Initial: 20mg every 6 hours. In some patients, a higher starting dose may be required. Doses should be adjusted to individual patient needs and should continue as long as indicated. Doses up to 160mg every 6 hours have been administered to some adult patients with severe Zollinger-Ellison Syndrome.
