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Amlodipine should be used with caution in patients with hypotension, poor cardiac reserve, heart failure.
The drug should not be used in cardiogenic shock, in patients who have suffered a myocardial infarction in the previous 2 to 4 weeks, or in acute unstable angina, in treatment of an anginal attack in chronic stable angina.
In patients with severe aortic stenosis, amlodipine may increase the risk of developing heart failure. Sudden withdrawal of amlodipine might be associated with an exacerbation of angina.
The dose may need to be reduced in patients with hepatic impairment.
