Spirolon Drug Interactions

Patients must be advised to inform the doctor or pharmacist if they are taking, have recently taken or might take any other medicines. The dose of Spirolon may be altered if they are taking any of the following: digoxin or carbenoxolone; medicines for high blood pressure including angiotensin-converting enzyme (ACE) inhibitors; other diuretics; non-steroidal anti-inflammatory drugs (NSAID) such as aspirin, indomethacin, mefenamic acid or ibuprofen; potassium supplements; antipyrine; heparin or low molecular weight heparin (medicines used to prevent blood clots); medicines known to cause hyperkalaemia (raised blood potassium levels); trimethoprim and trimethoprim-sulfamethoxazole.
Spirolon reduces the patient's responsiveness to noradrenaline. If the patient is going to have an operation where they will be given an anesthetic, they must be advised to inform the doctor in charge that they are taking Spirolon. Patients must be advised to inform the doctor if they are using abiraterone for the treatment of prostate cancer.
Spirolon with food, drink and alcohol: See Dosage & Administration.