Qlaira should not be used if the patient has any of the following conditions. If any of the listed conditions are present, the doctor must be advised. The doctor will discuss other form of birth control that would be more appropriate.
Qlaira should not be taken: if the patient has (or has ever had) a blood clot in a blood vessel of the legs (deep vein thrombosis, DVT), the lungs (pulmonary embolus, PE) or other organs; has a disorder affecting the blood clotting - for instance, protein C deficiency, protein S deficiency, antithrombin-III deficiency, Factor V Leiden or antiphospholipid antibodies; if an operation is needed or if the patient is off her feet for a long time (see Blood clots under Precautions); has ever had a heart attack or a stroke; has (or has ever had) angina pectoris (a condition that causes severe chest pain and may be a first sign of a heart attack) or transient ischaemic attack (TIA - temporary stroke symptoms); has any of the following diseases that may increase the risk of a clot in the arteries: severe diabetes with blood vessel damage, very high blood pressure, a very high level of fat in the blood (cholesterol or triglycerides), a condition known as hyperhomocysteinaemia; has (or has ever had) a type of migraine called 'migraine with aura'; has (or has ever had) liver disease and the liver function is still not normal; has (or has ever had) a tumour of the liver; has (or has ever had) cancer or suspected cancer of the breast or genital organs; has any unexplained bleeding from the vagina; allergic (hypersensitive) to estradiol valerate or dienogest, or any of the other ingredients of this medicine (listed in Description). This may cause itching, rash or swelling.