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Do not use Protaphane: In insulin infusion pumps; If you are allergic (hypersensitive) to human insulin or any of the other ingredients in Protaphane; If you suspect hypoglycaemia (low blood sugar) is starting; If it has not been stored correctly or been frozen; If the resuspended insulin does not appear uniformly white and cloudy.
Do not use Protaphane vial if the protective cap is loose or missing. Each vial has a protective, tamper-proof plastic cap. If it is not in perfect condition when you get the vial, return the vial to your pharmacy.
Do not use Protaphane Penfill if the cartridge or the device containing the cartridge is dropped, damaged or crushed.
Before using Protaphane: Check the label to make sure it is the right type of insulin.
Protaphane: Remove the protective cap.
Protaphane Penfill: Always check the cartridge, including the rubber stopper. Do not use it if any damage is seen or if there is a gap between the rubber stopper and the white label band. Take it back to your pharmacy. See your delivery system manual for further instructions.
Always use a new needle for each injection to prevent contamination.
Needles and Protaphane Penfill must not be shared.
How to use this insulin: Protaphane is administered by injection under the skin (subcutaneously). Never inject your insulin directly into a vein or muscle. Always vary the sites you inject within the same region, to reduce the risk of developing lumps or skin pitting. The best places to give yourself an injection are: your buttocks; the front of your thighs or upper arms.
How to inject Protaphane vial on its own or to mix with fast-acting insulin: Make sure you have the correct syringe with the corresponding unit scale for insulin injections.
Draw air into the syringe in the same amount as the dose of insulin you need.
Follow the instructions given by your doctor or nurse.
Just before injecting this insulin, roll the vial between your hands until the liquid is uniformly white and cloudy. Resuspending is easier if the insulin has reached room temperature.
Inject the insulin under the skin. Use the injection technique advised by your doctor or nurse.
Keep the needle under your skin for at least 6 seconds to make sure that the full dose has been delivered.
Resuspending the insulin: Protaphane Penfill: Resuspending is easier when the insulin has reached room temperature.
Before you put the Penfill cartridge into the insulin delivery system, move it up and down so that the glass ball moves from one end of the cartridge to the other at least 20 times. Repeat this movement at least 10 times before each injection. The movement must always be repeated until the liquid appears uniformly white and cloudy. Complete the other stages of injection without delay.
Check there are at least 12 units of insulin left in the cartridge to allow even resuspending. If there are less than 12 units left, use a new one.
How to inject Protaphane Penfill: Inject the insulin under the skin. Use the injection technique advised by your doctor or nurse as described in your delivery system manual.
Keep the needle under your skin for at least 6 seconds. Keep the push-button fully depressed until the needle has been withdrawn. This will ensure correct delivery and limit possible flow of blood into the needle or insulin reservoir.
After each injection, be sure to remove and discard the needle and store Protaphane without the needle attached. Otherwise the liquid may leak out which can cause inaccurate dosing.
Do not refill Protaphane Penfill.
Penfill cartridges are designed to be used with Novo Nordisk insulin delivery systems and NovoFine or NovoTwist needles. If you are treated with Protaphane Penfill and another insulin Penfill cartridge, you should use two insulin delivery systems, one for each type of insulin.
As a precautionary measure, always carry a spare insulin delivery system in case your Penfill is lost or damaged.
