Special precautions for disposal and other handling: Insulin preparations which have been frozen must not be used.
After removing Protaphane vial/Protaphane Penfill from the refrigerator, it is recommended to allow the vial/Penfill to reach room temperature before resuspending the insulin as instructed for first time use.
Insulin suspensions should not be used if they do not appear uniformly white and cloudy after resuspension.
Protaphane Penfill: Cartridges should only be used in combination with products that are compatible with them and allow the cartridge to function safely and effectively.
Needles and Protaphane Penfill must not be shared. The container must not be refilled.
The patients should be advised to discard the needle after each injection.
Incompatibilities: Insulin medicinal products should only be added to compounds with which it is known to be compatible. Insulin suspensions should not be added to infusion fluids.