Beta blockers can cause worsening heart failure (see Precautions). Since carvedilol has beta-blocking properties, care must be taken during initiation and up-titration of the drug in heart failure patients, since worsening heart failure has been observed during this phase of treatment. In order to minimize the risk of these events, it is critical to carefully follow the recommended dosing for pms-CARVEDILOL in patients with congestive heart failure (see Dosage & Administration).
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