pms-Aripiprazole Indications/Uses

pms-ARIPIPRAZOLE (aripiprazole) is indicated for the treatment of schizophrenia and related psychotic disorders in adults. In controlled clinical trials, aripiprazole was found to improve both positive and negative symptoms.
Aripiprazole has been shown to be more effective than placebo in maintaining clinical improvement for up to 26 weeks in adults.
Pediatrics (<18 years of age): When prescribing to adolescents with schizophrenia (15-17 years of age), clinicians must take into account the safety concerns associated with all antipsychotic drugs which include: weight gain; hyperlipidemia; hyperglycemia; and, extrapyramidal effects which can be more frequent or more severe in this patient population than in adults. pms-ARIPIPRAZOLE should only be prescribed to adolescents with schizophrenia by clinicians who are experienced in the diagnosis and treatment of adolescents with psychiatric illness and who are experienced in the early detection and management of the previously mentioned safety issues associated with this class of drugs.
Schizophrenia: pms-ARIPIPRAZOLE is indicated for the treatment of schizophrenia in adolescents 15-17 years of age.
Safety and efficacy were evaluated in one 6-week clinical trial in adolescents (13-17 years of age) with schizophrenia. pms-ARIPIPRAZOLE is not indicated for the treatment of schizophrenia in adolescents less than 15 years of age due to insufficient safety and efficacy data.
The safety and efficacy of aripiprazole during long-term treatment have not been systematically evaluated in adolescents with schizophrenia. The physician who elects to use pms-ARIPIPRAZOLE for extended periods in adolescents with schizophrenia should periodically re-evaluate the long-term usefulness of the drug for the individual patient.
Geriatrics: Geriatrics (≥65 years of age): pms-ARIPIPRAZOLE is not indicated in elderly patients with dementia. The safety and efficacy of aripiprazole in patients 65 years of age or older has not been established. Caution should be used when treating geriatric patients.