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In adults, somnolence, tachycardia, and headache have been reported with overdoses greater than 10 mg. In the event of overdosage, general symptomatic and supportive measures should be initiated promptly and maintained for as long as necessary.
Treatment of overdosage would reasonably consist of emesis (ipecac syrup), except in patients with impaired consciousness, followed by the administration of activated charcoal to absorb any remaining drug. If vomiting is unsuccessful, or contraindicated, gastric lavage should be performed with normal saline. Saline cathartics may also be of value for rapid dilution of bowel contents. Loratadine is not eliminated by haemodialysis. It is not known if loratadine is eliminated by peritoneal dialysis.
