Pregnancy: There is no evidence of the safety of pentamidine diisetionate in human pregnancy. A miscarriage within the first trimester of pregnancy has been reported following aerosolised prophylactic administration. Pentamidine diisetionate should not be administered to pregnant patients unless considered essential.
Lactation: The use of pentamidine diisetionate is contra-indicated in breast feeding mothers unless considered essential by the physician.
Fertility: There are no data on the effects of pentamidine on fertility in animals or humans.