Do not use Nitrolingual Spray in patients with hypersensitivity (allergy) to glyceryl trinitrate, other nitrate compounds, peppermint oil or any of the other ingredients of this medicine (listed in Description).
Do not use Nitrolingual Spray in cases of acute circulatory failure (shock, circulatory collapse and forms of shock caused by a reduction in circulating blood volume).
Do not use Nitrolingual Spray in patients with very low blood pressure (marked hypotension), i.e. systolic blood pressure below 90 mmHg.
Do not use Nitrolingual Spray in cases of shock triggered by heart failure (cardiogenic shock), unless there are appropriate measures in place to ensure a sufficiently high filling pressure in the heart (left-ventricular end diastolic pressure).
Do not use Nitrolingual Spray in patients with heart muscle disease with narrowing of the heart's inner chambers (hypertrophic, obstructive cardiomyopathy).
Do not use Nitrolingual Spray in disorders associated with increased pressure inside the skull (e.g. head injuries, bleeding on the brain) (however, a further increase in pressure has so far only been observed when high doses of glyceryl trinitrate were administered into a vein).
Do not use Nitrolingual Spray in patients with severe anaemia.
Do not use Nitrolingual Spray in patients taking certain medicines (phosphodiesterase-5 inhibitors, e.g. sildenafil, vardenafil or similar products) for the treatment of erection problems (erectile dysfunction) or certain disorders of the blood vessels in the lung (pulmonary arterial hypertension), as these can significantly increase the blood pressure-lowering effect of Nitrolingual Spray. Therefore, patients with coronary heart disease should note the restrictions on the use of such medicines or talk to their doctor before taking such medicines. Similarly, do not use Nitrolingual Spray in patients who have taken these medicines (phosphodiesterase-5 inhibitors) and develop acute chest pain.