The available experience indicates that, in general, drug interference with the contraceptive efficacy of Mona Lisa CuT 380A is highly unlikely. However, published reports appear to show diminished efficacy with long term use of non-steroidal anti-inflammatory drugs (especially acetyl salicylic acid) and of corticosteroids. Short term use in the treatment of dysmenorrhoea with non-steroidal anti-inflammatory drugs does not appear to reduce contraceptive efficacy.
Do not perform diathermy (short wave and microwave) of the sacral or abdominal region since heating may cause heat injury to the surrounding tissue.