Risk of GI distress or diarrhea. Caution in dehydrated patients & in patients w/ renal disease. When used as laxatives, Mg supplements are contraindicated in patients w/ GI obstruction & ileus.
May bind w/ Na polystyrene sulfonate; cellulose Na phosphate or edetate disodium. Increased excretion w/ excessive intake of ethanol or glucose. Possible increase in serum conc w/ oral Ca-containing medications in susceptible patients, primarily patients w/ renal insufficiency. Diuretics may interfere w/ the kidney's ability to regulate Mg levels. Risk of Mg toxicity w/ other Mg-containing antacids or laxatives, especially in patients w/ renal insufficiency. Formation of nonabsorbable complexes w/ oral quinolones or tetracycline antibiotics. May prevent absorption of oral etidronate. Increased serum conc w/ vit D analogs in patients w/ chronic renal failure.
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