Karbis Drug Interactions

Patients must be advised to inform the doctor or pharmacist if they are taking, have recently taken or might take any other medicines.
Karbis can affect the way some other medicines work and some medicines can have an effect on Karbis. If the patient is using certain medicines, blood tests may be needed to be done from time to time.
In particular, advise patients to inform the doctor if they are using any of the following medicines. The dose may be needed to change and/or other precautions to be taken: Other medicines to help lower the blood pressure, including beta-blockers, diazoxide and ACE-inhibitors such as enalapril, captopril, lisinopril or ramipril; Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, naproxen or diclofenac, celecoxib or etoricoxib (medicines to relieve pain and inflammation); Acetylsalicylic acid (if it is taken more than 3 g each day) (medicine to relieve pain and inflammation); Potassium supplements or salt substitutes containing potassium (medicines that increase the amount of potassium in the blood); Heparin (a medicine for thinning the blood); Co-trimoxazole (an antibiotic medicine) also known as trimethoprim/sulfamethoxazole; Water tablets (diuretics); Lithium (a medicine for mental health problems); If the patient is taking an ACE-inhibitor or aliskiren (see also information under Contraindications and Precautions); Clinical trial data has shown that dual blockade of the RAAS through the combined use of ACE-inhibitors, angiotensin II receptor blockers or aliskiren is associated with a higher frequency of adverse events such as hypotension, hyperkalaemia and decreased renal function (including acute renal failure) compared to the use of a single RAAS-acting agent; If the patient is being treated with an ACE-inhibitor together with certain other medicines to treat heart failure, which are known as mineralocorticoid receptors antagonists (MRA) (for example spironolactone, eplerenone).
Karbis with food, drink and alcohol: Karbis can be taken with or without food.
When Karbis is prescribed, advise the patient to discuss with the doctor before drinking alcohol. Alcohol may make the patient feel faint or dizzy.