Karbis Dosage/Direction for Use

Always take this medicine exactly as prescribed. Advise patient to check with the doctor or pharmacist if not sure. It is important to keep taking Karbis every day.
Karbis can be taken with or without food. The tablet should be swallowed with a drink of water. Advise patient to try to take the tablet at the same time each day. This will help the patient to remember to take it.
High blood pressure: The recommended dose of candesartan cilexetil is 8 mg once a day. This dose may be increased to 16 mg once a day and further up to 32 mg once a day depending on blood pressure response.
In some patients, such as those with liver problems, kidney problems or those who recently have lost body fluids, e.g., through vomiting or diarrhoea or by using water tablets, a lower starting dose may be prescribed.
Some black patients may have a reduced response to this type of medicine, when given as the only treatment, and these patients may need a higher dose.
Use in children and adolescents with high blood pressure: Children 6 to under 18 years of age: The recommended starting dose is 4 mg once daily.
For patients weighing <50 kg: In some patients whose blood pressure is not adequately controlled, the dose may be needed to be increased to a maximum of 8 mg once daily.
For patients weighing ≥50 kg: In some patients whose blood pressure is not adequately controlled, the dose may be needed to be increased to 8 mg once daily and to 16 mg once daily.
Heart failure in adults: The recommended starting dose of candesartan cilexetil is 4 mg once a day. The dose may be increased by doubling the dose at intervals of at least 2 weeks up to 32 mg once a day. Karbis can be taken together with other medicines for heart failure, and the doctor will decide which treatment is suitable for the patient.
Karbis 8 mg and 16 mg tablets cannot be divided, therefore Karbis 8 mg tablets are not suitable for patients who require a dose of 4 mg candesartan cilexetil. For these patients, other candesartan cilexetil preparations should be considered.
Forgotten intake of Karbis: A double dose should not be taken to make up for a forgotten dose. The next dose should be taken as normal.
Stopping intake of Karbis: If taking Karbis is stopped, the blood pressure may increase again. Therefore, advise the patient not to stop taking Karbis without first talking to the doctor.
Patients must be advised of any further questions on the use of this medicine.