Irbegen Plus Drug Interactions

Other medicines and Irbegen Plus: Patients should exercise caution if they are taking, have recently taken or might take any other medicines.
Diuretic agents such as the hydrochlorothiazide contained in Irbegen Plus may have an effect on other medicines. Preparations containing lithium should not be taken with Irbegen Plus without close medical supervision.
The dose may need to be changed and/or other precautions may need to be taken if an ACE inhibitor or aliskiren is being taken (see also Contraindications and Precautions).
Clinical trial data has shown that dual blockade of RAAS through the combined use of ACE inhibitors, angiotensin II receptor blockers or aliskiren is associated with a higher frequency of adverse events such as hypotension, hyperkalaemia and decreased renal functions (including acute renal failure) compared to the use of a single RAAS-acting agent.
Blood checks may be needed if the following are being taken: potassium supplements; salt substitutes containing potassium; potassium-sparing medicines or other diuretics; some laxatives; antigout medicines; therapeutic vitamin D supplements; medicines to control heart rhythm; antidiabetic medicines (oral agents as repaglinide or insulins); carbamazepine.
It is also important to know if the following are being taken: other antihypertensive medicines, steroids, anticancer medicines, painkillers, arthritis medicines, or cholestyramine and colestipol resins.
Irbegen Plus with food and drink: Irbegen Plus can be taken with or without food.
Due to the hydrochlorothiazide contained in Irbegen Plus, if alcohol is consumed while on treatment with this medicine, an increased feeling of dizziness may occur on standing up, especially when getting up from a sitting position.