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Patients should always check the pack and the label of the pre-filled pen for the name and type of the insulin when they get it from their pharmacy. Patients should make sure they get the Humalog Mix25 KwikPen/Humalog Mix50 KwikPen that their doctor has told them to use.
Patients whose blood sugar levels are well controlled by their current insulin therapy may not feel the warning symptoms when their blood sugar is falling too low. Patients must think carefully about when to have their meals, how often to exercise and how much to do. Patients must also keep a close watch on their blood sugar levels by testing their blood glucose often.
A few people who have had hypoglycaemia after switching from animal insulin to human insulin have reported that the early warning symptoms were less obvious or different. Patients who often have hypoglycaemia or have difficulty recognising them should have a discussion with their doctor.
Patients who have recently become ill, who have trouble with their kidneys or liver, or who are exercising more than usual should seek medical advice from their doctor, pharmacist or diabetes nurse.
The amount of insulin needed may also change if patients drink alcohol.
Patients should also tell their doctor, pharmacist or diabetes nurse if they are planning to go abroad. The time difference between countries may mean that patients have to have their injections and meals at different times from when they are at home.
Some patients with long-standing type 2 diabetes mellitus and heart disease or previous stroke who were treated with pioglitazone and insulin experienced the development of heart failure. Patients should inform their doctor as soon as possible if they experience signs of heart failure such as unusual shortness of breath or rapid increase in weight or localised swelling (oedema).
This Pen is not recommended for use by the blind or visually impaired without the help of someone trained to use the Pen.
Skin changes at the injection site: The injection site should be rotated to prevent skin changes such as lumps under the skin. The insulin may not work very well if it is injected into a lumpy area (see Side Effects). Patients should contact their doctor if they are currently injecting into a lumpy area before they start injecting a different area. Patients may be advised to check their blood sugar more closely, and to adjust the dose of their insulin or other antidiabetic medications.
Humalog Mix25 KwikPen/Humalog Mix50 KwikPen contains sodium: This medicine contains less than 1 mmol sodium (23 mg) per dose, that is to say essentially 'sodium-free'.
Driving and using machines: The ability to concentrate and react may be reduced in patients who have hypoglycaemia. This possible problem should be kept in mind in all situations where patients might put themselves and others at risk (e.g. driving a car or operating machinery). Patients should contact their doctor about the advisability of driving if they have: frequent episodes of hypoglycaemia; reduced or absent warning signs of hypoglycaemia.
