Entresto Contraindications

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage MIMS Class ATC Classification Regulatory Classification Presentation/Packing Brand Resources

The information highlighted (if any) are the most recent updates for this brand.

Full Prescribing Info

Contraindications

Hypersensitivity to the active substances, sacubitril, valsartan, or to any of the excipients.
Concomitant use with ACE inhibitors (see Precautions, Dosage & Administration and Interactions). Entresto must not be administered until 36 hours after discontinuing ACE inhibitor therapy.
Known history of angioedema related to previous ACE inhibitor or ARB therapy.
Hereditary angioedema.
Concomitant use with aliskiren-containing products in patients with diabetes mellitus or renal impairment (eGFR <60 ml/min/1.73 m²) (see Precautions and Interactions).
Pregnancy (see Use in Pregnancy & Lactation).
Severe renal impairment with eGFR <10 ml/min/1.73 m² and patients undergoing dialysis due to lack of data.

Entresto Contraindications

sacubitril + valsartan

Manufacturer:

Novartis

Distributor:

Zuellig