Enspryng Patient Counseling Information

Instructions for use: Read these instructions for use: Before you start using your pre-filled syringe; Each time you get a prescription refill, because it may contain new information.
This information does not take the place of talking to your doctor or nurse about your medical condition or treatment.
Your doctor or nurse will decide if you or a caregiver can give you injections of Enspryng at home. They will also show you or a caregiver the correct and safe way to use the syringe before you use it for the first time.
Talk to your doctor or nurse if you have any questions.
Important Information: Each syringe is pre-filled with a medicine called Enspryng.
Each carton of Enspryng contains only 1 pre-filled syringe.
Each pre-filled syringe can be used only once.
Do not share your syringes with other people.
Do not take the needle cap off until you are ready to inject Enspryng.
Do not use the syringe if it has been dropped or damaged.
Do not try to take the syringe apart at any time.
Do not leave the syringe unattended.
Do not re-use the same syringe.
Supplies needed to give your injection: Each Enspryng carton contains: 1 pre-filled syringe for one-time use only.
You also need the following but they are not included in the carton: 1 alcohol pad; 1 sterile cotton ball or gauze; 1 small bandage; 1 puncture-resistant sharps container for safe disposal of the needle cap and used syringe. See step 21 "Disposing of Enspryng" at the end of these instructions for use.
Prepare to use Enspryng: 1. Take the carton containing the syringe out of the refrigerator and place it on a clean, flat work surface (like a table).
2. Check the expiry date on the back of the carton. Do not use if the carton has expired.
3. Check that the front of the carton is sealed. Do not use if the seal is broken.
If the expiry date has passed or the seal is broken, go to step 21 "Disposing of Enspryng" as follows and contact your doctor or nurse.
Check expiration date (back). Check if carton is sealed.
4. Open the sealed carton.
5. Carefully lift the syringe out of the carton by holding the barrel.
Do not turn the carton upside down to remove the syringe.
Do not touch the activation guards. This may damage the syringe.
Do not hold the plunger or needle cap.
Check the syringe: 6. Check the expiry date on the syringe. Do not use the syringe if it has expired.
7. Check the syringe for any damage. Do not use if it is cracked or broken.
8. Check that the liquid through the viewing window is clear and colourless to slightly yellow. Do not inject the medicine if the liquid is cloudy, discoloured, or has particles in it.
There may be some small air bubbles in the syringe. This is normal and you should not try to remove them.
Check expiration date. Check liquid. Check syringe for damage.
If the expiry date has passed, the syringe is damaged or the liquid is cloudy, discoloured or has particles in it, do not use. Then go to step 21 "Disposing of Enspryng" as follows and contact your doctor or nurse.
Let your syringe get to room temperature: 9. Once you have checked the syringe, place it on a clean, flat work surface (like a table) for 30 minutes. This will allow it to reach room temperature.
It is important to let the syringe gently reach room temperature because injecting cold medicine may feel uncomfortable and make it harder to push the plunger.
Do not speed up the warming process by heating the syringe in any way.
Do not remove the needle cover while the syringe is reaching room temperature.
Wash your hands: 10. Wash your hands with soap and water.
Choose the injection site: 11. Choose your injection site in either: the lower part of your stomach (abdomen) or, the front and middle of your thighs.
Do not inject into the 5 cm area around your belly button.
Do not inject into moles, scars, bruises, or areas where the skin is tender, red, hard or broken.
Choose a different injection site for each new injection. Choose a different site for each new injection at least 2.5 cm away from the place used last time.
Clean the injection site: 12. Wipe the injection site with an alcohol pad and let it air dry.
Do not fan or blow on the area which you have cleaned.
Do not touch the injection site again before you give the injection.
Inject Enspryng: 13. Hold the barrel of the syringe between your thumb and index finger. With your other hand, pull the needle cap straight off. You may see a drop of liquid at the end of the needle. This is normal and will not affect your dose.
Use the syringe within 5 minutes of removing the cap or the needle may clog.
Do not take the needle cap off until you are ready to inject Enspryng.
Do not put the needle cap back on once it has been removed as this may damage the needle.
Do not touch the needle or let it touch any surfaces after removing the needle cap.
14. Throw away the needle cap in a puncture-resistant sharps container immediately. See step 21 "Disposing of Enspryng" as follows.
15. Hold the barrel of the syringe using your thumb and index finger. With your other hand, pinch the area of skin you have cleaned.
16. Use a quick, dart-like motion to insert the needle at an angle between 45° to 90°.
Do not change the angle of the injection while performing the injection.
Do not insert the needle again.
17. After the needle is inserted, let go of the pinched skin.
18. Slowly inject all of the medicine by gently pushing the plunger all the way down until it touches the activation guards.
19. Gently release the plunger and allow the needle to come out of the skin at the same angle it was inserted.
The needle will now be covered by the automatic needle-guard. If the needle is not covered, carefully place the syringe into a puncture-resistant sharps container to avoid injury. See step 21 "Disposing of Enspryng" as follows.
Taking care of the injection site: 20. There may be a little bleeding at the injection site. You can press a cotton ball or gauze over the injection site until any bleeding stops but do not rub it. If needed, you may also cover the area you injected with a small bandage. If the medicine comes into contact with your skin, wash the area with water.
Disposing of Enspryng: 21. Do not try to re-cap your syringe. Put your used syringe in a sharps disposal container immediately after use. Do not throw the syringe in your household waste and do not recycle it.
Ask your doctor or nurse or pharmacist for information about where you can get a "sharps" container or what other types of puncture-resistant containers you can use to safely dispose of your used syringes and needle caps.
Dispose of the used sharps disposal container as instructed by your healthcare provider or pharmacist.
Do not dispose of your used sharps disposal container in your household waste.
Do not recycle your used sharps disposal container.