For management of a suspected drug overdose, contact the doctor.
There is no specific antidote for overdose with EDURANT (rilpivirine). Human experience of overdose with EDURANT is limited. Treatment of overdose with EDURANT consists of general supportive measures including monitoring of vital signs and ECG (QT interval) as well as observation of the clinical status of the patient. Since rilpivirine is highly protein bound to plasma protein, dialysis is unlikely to result in significant removal of the active substance.