Co-administration of EDURANT is contraindicated with drugs which induce CYP3A enzymes or increase gastric pH as this may result in significant decreases in the plasma concentrations of rilpivirine, a loss of virologic response and possible resistance to EDURANT and to the NNRTI class of antiretrovirals. These drugs are listed in Table 7 (see Drug-Drug Interactions: Table 11 under Interactions). (See Table 7.)
