Curosurf Adverse Reactions

Treatment with CUROSURF may cause: Uncommon undesirable effects (affecting less than 1 in 100 people): severe infection (sepsis); bleeding inside the skull (intracranial); presence of air in the pleura (pneumothorax).
Rare undesirable effects (affecting less than 1 in 1000 people): low blood pressure (hypotension), reduced heart rate (bradycardia); chronic lung disease (bronchopulmonary dysplasia); pulmonary haemorrhage; reduced oxygen in blood (reduced oxygen saturation).
Unknown undesirable effects (their frequency cannot be estimated from available data): Difficulty in breathing with respiratory pauses (apnoea); oxygen poisoning (hyperoxia); bluish discoloration of skin and mucous membranes (neonatal cyanosis); abnormal electroencephalogram; complications due to endotracheal intubation.
Some cases of patent ductus arteriosus have been reported in new-borns treated with CUROSURF.
Some moderate and transient adverse events such as bradycardia, apnoea, reduced oxygen saturation, froth at the mouth, coughing, choking and sneezing were observed during the administration of CUROSURF with a thin catheter.
Do not use beyond the expiry date reported on the packaging materials.
Reporting undesirable effects: If the patient experiences any undesirable effects, including those not listed in this monograph, ask the doctor or pharmacist.