Carboplatin-Tranet Special Precautions

Caution should be exercised before using Carboplatin Infusion in: patients who are pregnant or with a chance of being pregnant; patients who are breast-feeding; patients with mild renal disease (patients should be monitored more regularly); patients who are elderly (over 65 years old); patients who have been treated with cisplatin or similar anti-cancer medicines in the past (carboplatin may cause abnormalities in the nervous system, such as pins and needles or hearing and vision problems) (patients may be regularly assessed); patients with headache, altered mental functioning, seizures and abnormal vision from blurriness to vision loss; patients who develop extreme tiredness and shortness of breath with decreased number of red blood cells (haemolytic anaemia), alone or combined with low platelet count, abnormal bruising (thrombocytopenia) and kidney disease where little or no urine is passed (symptoms of haemolytic uraemic syndrome); patients with fever (temperature greater than or equal to 38°C), or chills, which could be signs of infection (patients may be at risk of getting an infection of the blood).
In some cases during treatment with carboplatin, patients will be given medicines which help reduce a potentially life-threatening complication known as tumour lysis syndrome, which is caused by chemical disturbances in the blood due to the breakdown of dying cancer cells that release their content to the bloodstream.
The Carboplatin Infusion vial stopper contains dry natural rubber (a derivative of latex), which may cause allergic reactions.
Driving and using machines: Patients should not drive or use machines if they experience any side effect which may lessen the ability to do so such as nausea, vomiting, worsening of eyesight, or changes to vision and hearing.