This product is not intended for treatment of pernicious anaemia or other megaloblastic anaemias where vitamin B12 is deficient. Neurologic involvement may develop or progress, receive supplemental folic acid and who are inadequately treated with vitamin B12. This product is not intended for treatment of severe specific deficiency. Pyridoxine may decrease the efficacy of levodopa in the treatment of parkinsonism. Therefore it should be used with caution in patients undergoing such therapy.