Apo-Varenicline Drug Interactions

Patients must be advised to inform the doctor or pharmacist if they are taking, have recently taken or might take any other medicines.
In some cases as a result of stopping smoking, with or without APO-VARENICLINE, an adjustment of the dose of other medicines may be necessary. Examples include theophylline (a medicine to treat breathing problems), warfarin (a medicine to reduce blood clotting), and insulin (a medicine to treat diabetes). If in doubt, advise the patient to consult the doctor or pharmacist.
If the patient has severe kidney disease, the patient should avoid taking cimetidine (a medicine used for gastric problems) at the same time as APO-VARENICLINE as this may cause increased blood levels of APO-VARENICLINE.
Use of APO-VARENICLINE with other therapies for smoking cessation: Advise the patient to consult the doctor before using APO-VARENICLINE in combination with other smoking cessation therapies.
APO-VARENICLINE with food and drink: There have been some reports of increased intoxicating effects of alcohol in patients taking APO-VARENICLINE. However, it is not known if APO-VARENICLINE actually increases alcohol intoxication.
There is limited clinical data on any potential interaction between alcohol and varenicline. There have been post marketing reports of increased intoxicating effects of alcohol in patients treated with varenicline.