Wk 1: One 0.5-mg tab once a day on days 1-3, then one 0.5-mg tab bd (once in the morning & once in the evening) on days 4-7. Wk 2 (days 8-14) & wk 3-12 (day 15 until end of treatment): One 1-mg tab bd (once in the morning & once in the evening). If smoking is stopped after 12 wk of treatment, an additional 12 wk of treatment w/ 1-mg tab bd may be recommended to help avoid returning back to smoking.
Stop treatment in case of signs & symptoms of serious allergic reaction. Reports of neuropsychiatric symptoms; new or worse CV problems; seizures; potentially life-threatening skin rashes (SJS & erythema multiforme). Risk of returning to smoking may be elevated in the period immediately following the end of treatment. Gradually lower dose at the end of treatment. May impair ability to drive or operate machinery. Caution in patients w/ history of psychiatric disorder; pre-existing CV problems; history of seizures or other conditions that potentially lower seizure threshold; kidney problems. Avoid use during pregnancy. May pass into breast milk. Not recommended in paed patients.
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