Overview
Pulmonary arterial hypertension is a syndrome resulting from restricted flow through the pulmonary arterial circulation resulting in increased pulmonary vascular resistance and remodeling, and ultimately leading to right heart failure.
It is a part of the spectrum of pulmonary hypertension which is a hemodynamic and pathophysiological condition.
Cardinal symptoms include progressive dyspnea on minor exertion, or when bending forward (bendopnea), exercise-induced abdominal distention and nausea, fatigue and rapid exhaustion, hemoptysis, palpitations, syncope during or shortly after physical exertion, and weight gain due to fluid retention.
Achievement and maintenance of a low-risk profile on optimized medical therapy is the recommended treatment goal in patients with pulmonary arterial hypertension.
The 3 step treatment strategy is composed of step 1 that includes general care, patient education, and supportive therapy, step 2 includes initiation of pharmacologic therapy and step 3 that includes pharmacologic combination therapy and interventional treatments depending on the patient's response to initial treatment.
For further information regarding the management of Pulmonary Arterial Hypertension, please refer to Disease Algorithm for the Treatment Guideline.
It is a part of the spectrum of pulmonary hypertension which is a hemodynamic and pathophysiological condition.
Cardinal symptoms include progressive dyspnea on minor exertion, or when bending forward (bendopnea), exercise-induced abdominal distention and nausea, fatigue and rapid exhaustion, hemoptysis, palpitations, syncope during or shortly after physical exertion, and weight gain due to fluid retention.
Achievement and maintenance of a low-risk profile on optimized medical therapy is the recommended treatment goal in patients with pulmonary arterial hypertension.
The 3 step treatment strategy is composed of step 1 that includes general care, patient education, and supportive therapy, step 2 includes initiation of pharmacologic therapy and step 3 that includes pharmacologic combination therapy and interventional treatments depending on the patient's response to initial treatment.
For further information regarding the management of Pulmonary Arterial Hypertension, please refer to Disease Algorithm for the Treatment Guideline.
