Đăng xuất
Pharmacological group: Bioflavonoids that protect the cardiovascular system. ATC code: C05CA53.
Pharmacology: Pharmacodynamics: The drug has a dual action on the vascular system returning to the heart.
In veins and venules, the drug reduces the stretchiness of the veins and reduces stagnation in the veins.
In the microcirculation, the drug normalizes capillary permeability and enhances capillary strength.
Pharmacokinetics: In humans, after oral dosing with carbone 14-labelled diosmine.
Excretion is mainly in the faeces and excretion in the urine averages about 14% of the dose.
The half-life is 11 hours.
The drug is extensively metabolised, which is recognized by the presence of various phenol acids in the urine.
