Sign Out
Decreased effect: Metabolized by the hepatic cytochrome P-450 enzymes; therefore, the drug's clearance and half-life may be changed with concomitant use of cytochrome P-450 inducers (eg, barbiturates, carbamazepine, rifampin, phenytoin, and phenylbutazone).
Increased toxicity: Inhibitors (eg, cimetidine, allopurinol, and disulfiram).
Continue with Google