ZEFXON INJECTION (omeprazole) is the proton/acid pump inhibitor which reduces gastric acid secretion by specific action; inhibition of the enzyme H+, K+-ATPase (The proton pump) in the parietal cell, the final step of acid secretion; thus inhibition acid secretion is occurred.
Pharmacokinetics: Onset of action: ~1 hour.
Duration: 72 hours.
Plasma protein binding: 95%.
Metabolism: by liver.
Excretion: as metabolites in urine, feces.
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