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Eptinezumab is not metabolized by cytochrome P450 enzymes. Therefore, interactions by eptinezumab with concomitant medications that are substrates, inducers, or inhibitors of cytochrome P450 enzymes are considered unlikely.
In healthy subjects, co-administration of a single dose of 300 mg eptinezumab administered as an intravenous infusion (over a period of 1 hour ± 15 min) with a single dose of 6 mg sumatriptan administered subcutaneously did not alter the pharmacokinetics of eptinezumab or sumatriptan.
Interactions with other drugs have not been studied.
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