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Use in Pregnancy: Pregnancy Category C.
There are no adequate and controlled studies to date using chlorpheniramine in pregnant women, and the drug should be used during the first 2 trimesters only when clearly needed.
Nursing Mothers: It is not known whether chlorpheniramine is distributed into milk, but other antihistamines (e.g., diphenhydramine) have been detected in milk. Because of the potential for serious adverse reactions to antihistamines in nursing infants, a decision should be made whether to discontinue nursing or chlorpheniramine, taking into account the importance of the drug to the woman.
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