Vastarel OD Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing Local Product Insert

Concise Prescribing Info

Contents

Trimetazidine diHCl

Indications/Uses

Add-on therapy for symptomatic treatment of adults w/ stable angina pectoris who are inadequately controlled by or intolerant to 1st-line anti-anginal therapies.

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Dosage/Direction for Use

80 mg once daily in the morning. Moderate renal impairment (CrCl 30-60 mL/min) Recommended dose: 35 mg in the morning.

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Overdosage

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Administration

May be taken with or without food: Swallow whole, do not open. Take during breakfast.

Contraindications

Hypersensitivity. Parkinson disease, parkinsonian symptoms, tremors, restless leg syndrome, & other related movement disorders. Severe renal impairment (CrCl <30 mL/min).

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Special Precautions

Not a curative treatment for angina attacks, nor as initial treatment for unstable angina or MI, nor in pre-hospital phase or during 1st days of hospitalisation. W/draw treatment immediately if signs & symptoms suggestive of severe cutaneous adverse reactions including DRESS & acute generalized exanthematous pustulosis (AGEP) occur. May cause or worsen parkinsonian symptoms (tremor, akinesia, hypertonia). Falls related to gait instability or hypotension particularly in patients taking antihypertensives. Assess treatment benefit after 3 mth & discontinue if there is no treatment response. Closely monitor for skin reactions. May give +ve result in anti-doping test in athletes. Not to be taken by patients w/ fructose intolerance, glucose-galactose malabsorption or sucrose-isomaltase insufficiency. May affect ability to drive & use machines. Moderate renal impairment. Avoid use during pregnancy. Not to be used during lactation. Childn <18 yr. Elderly >75 yr.

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Use In Pregnancy & Lactation

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Adverse Reactions

Dizziness, headache; abdominal pain, diarrhoea, dyspepsia, nausea & vomiting; rash, pruritus, urticaria; asthenia. DRESS, AGEP.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Vastarel OD detailed prescribing information

Storage

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Description

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Action

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MIMS Class

Anti-Anginal Drugs

ATC Classification

C01EB15 - trimetazidine ; Belongs to the class of other cardiac preparations.

Thai FDA Category

Presentation/Packing

Form

Vastarel OD PR cap 80 mg

Packing/Price

3 × 10's

Vastarel OD

trimetazidine

Manufacturer:

Servier

Distributor:

DKSH