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Pregnancy: Vancomycin crosses the placenta and can be detected in fetal serum amniotic fluid, and cord blood. Adverse fetal effects, including sensorineural, hearing loss or nephrotoxicity, have not been reported following maternal use during the second or third trimesters of pregnancy.
Lactation: Vancomycin is distributed into milk following IV administration. Vancomycin exhibits minimal oral absorption; therefore, the amount available to pass into the milk would be limited following oral administration.
However, IV and oral Vancomycin should be used with caution in nursing women. Because of the potential for serious adverse reactions from the drug in nursing infants, a decision should be made whether to discontinue nursing or the drug, taking into account the importance of Vancomycin to the woman.
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