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Adjunctive treatment of severe systemic fungal infection caused by susceptible strains of Candida or Cryptococcus.
Flucytosine is used for the treatment of chromoblastomycosis caused by susceptible fungi.
Flucytosine should be used in combination with amphotericin B for the treatment of candidiasis and cryptococcosis because of rapid emergence of resistance to Flucytosine in Candida and Cryptococcus isolated in patients receiving Flucytosine alone.
Combination with amphotericin B is often synergistic.
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