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TISSEEL Fibrin Sealant with Synthetic Aprotinin alone is not indicated for the treatment of massive and brisk arterial or venous bleeding.
TISSEEL Fibrin Sealant with Synthetic Aprotinin is not indicated to replace skin sutures intended to close surgical wound.
TISSEEL Fibrin Sealant with Synthetic Aprotinin must never be applied intravascularly. Intravascular application may result in life-threatening thromboembolic events.
TISSEEL Fibrin Sealant with Synthetic Aprotinin must not be applied in case of hypersensitivity to the active substances or to any of the excipients.
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