Cream: In controlled clinical studies, the incidence of adverse reactions was low (0.8%) for desoximetasone emollient cream 0.25% and included burning, folliculitis, and follow-up pustular lesions. The incidence of adverse reactions was also 0.8% for desoximetasone emollient cream 0.05% and included pruritus, erythema, vesiculation, and burning sensation. The incidence of adverse reactions was low (0.3%) for desoximetasone ointment 0.25% and consisted of development of comedones at the site of application.
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