This medication should not be used in the presence of any the conditions listed as follows. Should any of the conditions appear for the first time during use, the product should be stopped immediately: Renal insufficiency; Hepatic dysfunction; Adrenal insufficiency; Thrombophlebitis or thromboembolic disorders; A past history of deep-vein thrombophlebitis or thromboembolic disorders; Active or history of cerebrovascular disease or coronary artery disease; Valvular heart disease with thrombogenic complications; Severe hypertension; Diabetes with vascular involvement; Have or have had a pancreatitis associated with high levels of fatty substances in blood; Headaches with focal neurological symptoms; Major surgery with prolonged immobilization; Known or suspected breast carcinoma, or endometrium carcinoma; Known or suspected estrogen-dependent neoplasia; Cholestatic jaundice of pregnancy or jaundice with prior pill use; Known or suspected pregnancy; Undiagnosed vaginal bleeding; Liver tumor (benign or malignant) or active liver disease; Jaundice; Heavy smoking (≥15 cigarettes per day) and over age 35; Hypersensitivity to any component of this product.