Recommended Dose: Adult: Initial dosage: Single dose of 50 mg tablet. If the headache returns or the patient has a partial response to the initial dose, the dose may be repeated after 2 hours, not to exceed a total daily dose of 200 mg.
Maximum dose: 200 mg/day.
Hepatic function impairment: Mild to moderate hepatic impairment: Bioavailability is increased with liver disease. If treatment is needed, do not exceed single doses of 50 mg.
Children and adolescents (under 18 years of age): The efficacy of sumatriptan tablets in this population has not been demonstrated.
Elderly (over 65 years of age): Experience of the use of sumatriptan tablets in patients aged over 65 years is limited. The pharmacokinetics do not differ significantly from a younger population, but until further clinical data are available, the use of sumatriptan tablets in patients aged over 65 years is not recommended.
Mode of Administration: Sumigran is administered orally. It is advisable that sumatriptan be given as early as possible after the onset of a migraine headache, although it is equally effective at whatever stage of the attack it is administered.
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