Sixime Dosage/Direction for Use

Mode of administration: Cefixime is administered orally, with or without food.
Recommended Dose: Adult Dosage: Cefixime is given orally in dose of 100 to 400 mg daily as a single dose or in two divided doses. The dose and duration of usage depend on the disease and severity of the disease or to be used as directed by the physician. The highest dose is 400 mg/day.
Otitis media: 400 mg once daily or 200 mg every 12 hours for 10-14 days.
Pharyngitis and tonsillitis: 400 mg once daily or 200 mg every 12 hours for at least 10 days.
Respiratory tract infections and Urinary tract infections: 400 mg once daily or 200 mg every 12 hours for 5-10 days.
Gonorrhea and associated infections: Uncomplicated gonorrhea: 400 mg single dose.
Uncomplicated cervical, urethral, rectal gonorrhea infection: 400 mg single dose plus azithromycin 1 g orally single dose.
Children dosage: Cefixime can be used in children 6 months to 12 years of age. The recommended children dose is 8 mg/kg daily given in 1 or 2 divided doses for the treatment of mild to moderate infections. The dose and duration of usage depend on the disease and severity of the disease or to be used as directed by the physician.
Typhoid: Children 6 months to 16 years of age have received Cefixime in a dosage of 5-10 mg/kg twice daily for 14 days.
Dosage in renal impairment: Oral doses of Cefixime should be reduced in patients with moderate to severe renal impairment according to creatinine clearance (CrCl). In the USA licensed product information recommended doses adjusted as follows: See table.

Click on icon to see table/diagram/image

Dosage in elderly patients: Modification of the usual dosage of Cefixime is not necessary in elderly patients base on age, but may be required because the age-related decreases in renal function.