Sibatam: Side Effects & Dosing

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing

Concise Prescribing Info

Contents

Sulbactam Na

Indications/Uses

Moderate to severe bacterial infections in combination w/ other parenteral β-lactam antibiotics eg, ampicillin.

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Dosage/Direction for Use

Adult 0.5-1 g every 6, 8, or 12 hr in combination w/ other β-lactam antibiotics. Max daily dose: 4 g. Multidrug resistant or life-threatening Acinetobacter baumanii infection 6 g Sulbactam alone daily in divided doses. Ped 50 mg/kg daily every 6, 8, or 12 hr in combination w/ other β-lactam antibiotics. Max daily dose: 80 mg/kg.

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Overdosage

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Contraindications

Hypersensitivity to sulbactam or β-lactam antibiotics.

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Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Sibatam detailed prescribing information

Special Precautions

History of hypersensitivity reactions. Allergic reactions & fatal hypersensitivity. Discontinue if rash, skin irritation, or swelling occur. Consider Na content in patients w/ electrolyte disorders. Periodically check for organ system (eg, renal, hepatic & hematopoietic) dysfunction during extended therapy. Renal & hepatic impairment. Pregnancy & lactation. Childn <1 yr. Elderly.

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Use In Pregnancy & Lactation

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Adverse Reactions

Eosinophilia, dizziness, diarrhea, increased transaminase levels & thrombophlebitis. Fungal infections of oral mucosa membrane, stomatitis, pseudomembranous colitis; thrombocytopenia, leucopenia, increased platelet, leukocytosis, neutropenia, anemia, prolonged bleeding time, speckled skin or mucosal bleeding (purpura); hypersensitivity reaction, anaphylactic shock; headaches, seizures; vomiting, stomach upset, GI pain, nausea, decreased appetite & bleeding; increased serum bilirubin conc; SJS, TEN; muscle cramps; increased serum creatinine, interstitial nephritis; inj site pain.

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Drug Interactions

Physically &/ or chemically incompatible w/ aminoglycosides. Increased serum t_½ w/ oral probenecid.

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Storage

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Description

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Action

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MIMS Class

Other Beta-Lactams

ATC Classification

J01CG01 - sulbactam ; Belongs to the class of beta-lactamase inhibitors. Used in the systemic treatment of infections.

Thai FDA Category

Presentation/Packing

Form

Sibatam powd for inj 0.5 g

Packing/Price

1's

Form

Sibatam powd for inj 2 g

Packing/Price

1's

Sibatam

sulbactam

Manufacturer:

Siam Bheasach

Distributor:

Siam Pharmaceutical

Marketer:

Siam Pharmaceutical