Siamformet Dosage/Direction for Use

SIAMFORMET should be taken with meals, 1-2 tablets once or twice a day, or as directed by the physicians. In concurrent therapy with either a sulphonylurea or insulin, blood glucose level should be checked, due to the possibility of hypoglycemia.
Initially, the dosage should be 1-2 tablets once or twice a day. Dosage should be gradually increased up to 4 tablets a day until diabetic control is obtained, then dosage reduction is possible.
When administered with a sulfonylurea, the initial dosage for SIAMFORMET is 1 tablet a day. The dosage of SIAMFORMET should be gradually increased until diabetic control is obtained. The dosage of sulfonylurea may then be reduced or even withdrawn, and SIAMFORMET can be continued as a sole therapy.
Administering with insulin: 1. When the dosage of insulin is less than 60 units a day, 1 tablet should be added initially, followed by gradual reduction of the insulin (4 units every 2-4 days).
2. When the dosage of insulin is more than 60 units a day, the addition of SIAMFORMET may cause a rapid reduction of blood glucose level. Close monitoring of patients is advised in the first 24 hours after the addition of SIAMFORMET. After this period, the recommendations in 1 should be followed.