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Use caution in patients with cardiovascular disease (arrhythmia or hypertension or heart failure), convulsive disorders, diabetes, glaucoma, hyperthyroidism, or hypokalemia.
Beta-agonists may cause elevation in blood pressure, heart rate, and result in CNS stimulation/excitation. Beta2-agonists may increase risk of arrhythmia, increase serum glucose, or decrease serum potassium.
Consumption of large quantities of guaifenesin-containing medications may be associated with an increased risk of drug-induced kidney stone formation.
Doses of guaifenesin larger than those required for expectorant action may produce emesis.
Unless directed by a physician, guaifenesin should not be used for persistent or chronic cough. A persistent cough may be indicative of a serious conditions.
Before prescribing medication to suppress or modify cough, it is important to ascertain that the underlying cause of cough is identified.
