Planil 2X Gel Use In Pregnancy & Lactation

The systemic concentration of diclofenac is lower after topical administration, compared to oral formulations. With reference to experience from treatment with NSAIDs with systemic uptake, the following is recommended: Pregnancy: Since NSAIDs, such diclofenac, inhibit the synthesis of prostaglandin which could affect with laboring, pregnancy prolongation, and fetal renal function, the treatment should avoid during the last trimester of pregnancy.
PLANIL 2X GEL should be used during the first two trimesters of pregnancy, only if the expected benefit justifies the potential risk to the fetus.
Breast-feeding: The excretion of the topical diclofenac in breast milk is unknown; however, regards to the distribution of diclofenac, small amount can be distributed into breast milk. Therefore, PLANIL 2X GEL should only be used during lactation if the expected benefit justifies the potential risk to the new born. If there are compelling reasons for using it, it should not be applied to the breasts or to large areas of skin, nor should it be used for a prolonged period.